Technologies

Establishment of services in Naver Cloud Platform considering data security

Cloud's serucity services

We are using IPS, IDS, WAF, and Anti-Virus security services for security monitoring activities other than the cloud basic security system.

Ensure data security

Utilizing the cloud database, we secured the availability and integrity of data collected through devices such as storage self-encryption, redundant configuration, automatic backup, and dissipative backup to other regions.

Information protection activities

ISO 27001

After the initial certification of the International Standard for Information Security Management System, re-certification was completed in March 2022. This means that ichrogene is certified for the overall level of security.

CSA Star

As a global security certification that measures the cloud-based gene service competency level, re-certification was completed in March 2022 after the initial certification. This means that security management activities are being carried out effectively for cloud-based services.

Regular monitoring activities

In preparation for physical or technical accidents, we automate service inspections through web service monitoring and analyze activity logs to periodically monitor and supplement to see if there are any intrusions or failures.Only authorized persons can access the personal information processing system, and the database in which customer information is stored is logged in real time through access control. In addition, security activities such as installing vaccines on work terminals and monitoring data utilization are performed regularly or when necessary.

This is a patent information for type 2 diabetes premium service.

  • Korea Centers for Disease Control and Prevention

    The National Institutes of Health, the Korea Centers for Disease Control and Prevention, is an institution affiliated with the Ministry of Health and Welfare that conducts health and medical research and development to prepare for and respond to the risk of infectious diseases and chronic diseases. .

  • Patent
    Information

    This report was developed by technology transfer of a patent (Patent No. 10-2254341) related to a method for diagnosing risk groups for type 2 diabetes conducted by the National Institutes of Health, Korea Centers for Disease Control and Prevention.

  • calculation
    method

    ∑G×A
    Genetic risk is predicted by summing the genetic effect (G) of a total of 231 genetic variants multiplied by the number of alleles with influence (A) within an individual's unique genotype.

Analysis methods

Based on the genetic information of more than 150,000 Koreans, we analyze the genetic risk of type 2 diabetes using 175 genetic mutations related to type 2 diabetes and 56 genetic mutations related to fasting blood sugar.

The high risk group (top 1%) with the highest genetic risk of fasting blood sugar has a 2.27 times higher risk of developing type 2 diabetes compared to the general population, and the highest genetic risk group for type 2 diabetes has a 4.58 times higher risk.

In particular, the risk of developing type 2 diabetes increases by 8.08 times in the complex high-risk group with both high fasting blood glucose and high genetic risk of type 2 diabetes. This report predicts the onset of type 2 diabetes by single analysis of ① fasting blood sugar and ② genetic risk of type 2 diabetes, and ③ integrated analysis of each result to provide more accurate results.

Genetic risk of high fasting blood sugar

Type 2 diabetes genetic risk

Integrated genetic risk

Result of risk analysis of type 2 diabetes by the Korea Centers for Disease Control and Prevention

Analysis type Target item Genetic Risk OR (odds ratio) 95% confidence interval statistical significance(p-value)
Single fasting blood sugar Top 20% 1.67 1.57-1.77 8.96E-66
Top 10% 1.9 1.77-2.04 4.45E-59
Top 5% 2.04 1.87-2.23 4.65E-59
Top 1% 2.27 1.92-2.69 3.38E-21
type 2 diabetes Top 20% 2.27 2.14-2.40 1.39E-173
Top 10% 2.88 2.70-3.08 8.28E-221
Top 5% 3.43 3.17-3.71 2.71E-204
Top 1% 4.58 3.96-5.30 1.61E-93
Integration fasting blood sugar
+
type 2 diabetes
Top 20% 3.26 2.91-3.66 7.29E-91
Top 10% 4.34 3.79-4.97 1.54E-99
Top 5% 5.28 4.40-6.34 2.75E-71
Top 1% 8.08 4.55-14.35 9.33E-13

How to calculate the incidence rate

ichrogene's iDNADoctor premium report provides more accurate information by calculating the actual incidence rate by genetic risk (risk, average, good) based on epidemiological information and genotype information of 150,000 Koreans from the Korea Centers for Disease Control and Prevention.

  • ichrogene inc

    calculation method

    Your incidence rate = the actual incidence rate of those with the same age and genotype as you among 150,000 Koreans

    type 2 diabetes

    Genotype-incidence rate linkage

    Linking the actual incidence of a population with the same genotype as the tester

    Genetic Risk

    Provides incidence rates for all genetic risks

  • Company

    calculation method

    Your prevalence = the average prevalence of Koreans based on statistical data X your risk

    type 2 diabetes

    Genotype-incidence rate linkage

    Only average statistics that are independent of your genotype are reflected

    Integrated genetic risk

    Provides only your disease risk figure

  • Company

    calculation method

    Your prevalence = the average prevalence of Koreans based on statistical data X your risk

    type 2 diabetes

    Genotype-incidence rate linkage

    Only average statistics that are independent of your genotype are reflected

    Integrated genetic risk

    Provides only your disease risk figure

Prediction accuracy

iDNADoctor Premium Report has a high prediction accuracy of 85% by comparing the high-risk group (top 1%) predicted based on the genotype information of 150,000 Koreans from the Korea Centers for Disease Control and Prevention and the actual epidemiologic information.

(Examples)

division Genetic high risk group actual number of patients Prediction accuracy
Top 1% 100 85 85.0%
Top 5% 500 357 71.3%
Top 20% 2 1 60.0%

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